The tablets can be taken independently of meals.įor elderly and debilitated patients reduce the initial dose by approximately 50 % and adjust the dosage as needed and tolerated (see section 4.4). Premedication before diagnostic procedures or before surgical interventionsġ to 2.5 mg lorazepam on the evening before and/or 2 to 4 mg approximately 1 to 2 hours prior to the procedure. Treatment should therefore not be discontinued abruptly, but rather terminated by gradual dose reduction. It should be noted that, after prolonged periods of use (more than 1 week) and upon abrupt withdrawal of this medicinal product, sleep disorders, states of anxiety and tension, inner restlessness and agitation may temporarily recur in exaggerated form. After 2 weeks of daily intake, the physician should clarify by gradual dose reduction whether treatment with lorazepam is still indicated. For chronic illnesses, the duration of use depends on progression. Due to a delayed onset of effect and depending on the length of the sleeping period a hang-over effect might be possible during the following day (see Section 4.4).įor acute illnesses, the use of lorazepam should be limited to single doses or for a few days. If the daily dose is taken as single dose in the evening it should not be taken on a full stomach. If the main focus involves sleep disorders requiring treatment, the daily dose (0.5 to 2.5 mg lorazepam) can be taken as a single dose approximately half an hour before bedtime. In individual cases, especially in inpatient use, the daily dose can be increased to a maximum of 7.5 mg, taking all precautions into consideration. The daily dose is generally 0.5 to 2.5 mg lorazepam, divided into 2 to 3 single doses or as a single evening dose. Treatment of anxiety and sleep disorders caused by anxiety As a basic rule, the dose should be kept as low as possible and the duration of treatment as short as possible (not exceeding 4 weeks, including the tapering off process). The dose and duration of use must be adjusted to the individual response, therapeutic indication and the severity of the illness.
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